RESEARCH STUDY THE EFFECT OF COMBINATION : - AS RETATRUTIDE IS Triple agonist at GLP-1, GIP, and glucagon receptors. GLP-1 and GIP contribute satiety and improved glucose handling, while glucagon receptor activity may increase energy expenditure and support additional weight-loss effects. - CAGRILINTIDE ACT AS Long-acting amylin analogue. It slows gastric emptying, increases satiety, and reduces meal size through central and peripheral satiety . FOR RESEARCH USE ONLY